Use of Antibiotic Therapy Combined with Enamel Matrix Derivate Proteins as an Adjunct to Non-Surgical Periodontal Treatment: A Case Report
Keywords:
Periodontal treatment, Stage IV periodontitis, Enamel-derived matrix protein, Antibiotic therapyAbstract
Adjunctive therapies such as the use of systemic antimicrobials associated with the use of enamel matrix-derived proteins (EMDP) can contribute to the healing process and favor the formation of a new periodontal apparatus, as well as reducing non-responsive pockets. This case report aimed to compare the use of PDME associated with antibiotic therapy in treating non-responsive sites. Non-surgical treatment was carried out on a 54-year-old woman. After 3 months, scraping therapy with access surgery associated
with the use of PDME was carried out on elements 14, 15, and 16, and on elements 24, 25, and 26 only reinstrumentation was performed. At the same time, the patient underwent antibiotic therapy with amoxicillin and metronidazole for 14 days. A reduction in the average probing depth from 3.7 mm to 2.3 mm was observed. The use of antibiotic therapy and its association with the use of PDME showed clinical improvement in the periodontal aspect.